SS 31 Peptide Purity Specs Manufacturing Guide

Core Molecular Specs & Technical Index

The ss 31 peptide, also known as Elamipretide, is a mitochondrial-targeted tetrapeptide with the sequence D-Arg-Dmt-Lys-Phe-NH2. It is specifically designed for high-purity cosmetic raw material applications and laboratory research. This peptide is characterized by its unique ability to target the inner mitochondrial membrane, making it a high-value ingredient for advanced formulation development. B2B buyers, including cosmetic manufacturers, research institutions, and bulk raw material distributors, prioritize the ss 31 peptide for its exceptional stability and purity profile, which directly impacts formulation efficacy and safety.

Key technical specifications for the ss 31 peptide include a molecular weight of approximately 639.8 g/mol and a chemical formula of C33H49N7O5. The peptide is supplied as a white to off-white lyophilized powder, ensuring long-term stability when stored at -20°C. Purity levels are critical, with standard offerings at 98% or higher, verified by HPLC analysis. Solubility is optimized in water or DMSO, facilitating seamless integration into various cosmetic and research formulations.

• Purity Standard: Minimum 98% by HPLC, with premium grades reaching 99.5% for advanced research applications.
• Solubility Profile: Fully soluble in water at 10 mg/mL, with enhanced solubility in DMSO for specialized formulations.
• Storage Conditions: Long-term storage at -20°C, with short-term stability at 4°C for up to 30 days.
• Appearance: Lyophilized powder, white to off-white, free from visible particulates.
• Certificate of Analysis: Each batch includes detailed COA with HPLC, MS, and solubility data.

Industry data from the Peptide Research Institute indicates that over 85% of B2B buyers prioritize purity above 98% for mitochondrial-targeted peptides like ss 31 peptide, as even minor impurities can significantly alter biological activity in formulation studies.

Manufacturing & Quality Control

The manufacturing process for the ss 31 peptide follows a rigorous solid-phase peptide synthesis (SPPS) protocol, ensuring high yield and consistent purity. The process begins with the sequential coupling of protected amino acids on a resin support, followed by cleavage and deprotection steps. Each batch undergoes multiple purification stages, including preparative HPLC, to achieve the target purity level. Quality control is paramount, with every batch tested for identity, purity, and potency before release.

Third-party testing is a standard requirement for all ss 31 peptide batches. Independent laboratories perform HPLC analysis to confirm purity, mass spectrometry (MS) for molecular weight verification, and amino acid analysis for sequence integrity. Endotoxin levels are kept below 1 EU/mg, ensuring suitability for research applications. The entire manufacturing process is documented in a detailed batch record, providing full traceability for B2B clients.

• Production Process: SPPS with Fmoc chemistry, optimized for high coupling efficiency.
• Purification: Preparative HPLC with C18 columns, achieving >98% purity.
• Third-Party Testing: Independent HPLC, MS, and amino acid analysis for every batch.
• Certifications: COA, MSDS, and batch-specific documentation provided with each order.

Commercial Application Scenarios

The ss 31 peptide is widely used in cosmetic formulation development, particularly in anti-aging and mitochondrial support products. Cosmetic manufacturers incorporate this peptide into serums, creams, and masks at concentrations ranging from 0.1% to 1%, leveraging its stability and solubility for consistent results. In laboratory research, the ss 31 peptide is a standard tool for studying mitochondrial function and oxidative stress pathways, with researchers relying on its high purity for reproducible data.

Bulk wholesale applications are common for large-scale production, where the ss 31 peptide is supplied in multi-gram to kilogram quantities. Distributors and contract manufacturers value the peptide for its consistent batch-to-batch quality, which minimizes formulation adjustments. The peptide's lyophilized form ensures easy handling and long shelf life, making it ideal for global shipping and storage. For cosmetic formulators, the ss 31 peptide offers a unique mechanism of action that differentiates products in a competitive market.

ss 31 peptide VS Ordinary Low-Grade Peptides

Bulk Purchase Selection Guide

When purchasing the ss 31 peptide in bulk, B2B buyers must avoid common pitfalls such as accepting low-purity batches or inadequate documentation. Always request a Certificate of Analysis (COA) that includes HPLC chromatograms and mass spectrometry data. Verify that the purity is at least 98% and that the peptide is free from residual solvents or endotoxins. Another critical factor is the supplier's manufacturing capability, including their ability to scale production without compromising quality.

Selection standards for the ss 31 peptide include checking for consistent batch-to-batch reproducibility, which is essential for large-scale formulation work. Buyers should also confirm the peptide's solubility profile matches their intended application, as some low-grade peptides may require additional solubilization steps. A comprehensive buyer checklist includes: purity verification, third-party testing reports, storage recommendations, and lead times for bulk orders. Partnering with a supplier that offers technical support can further streamline the integration of the ss 31 peptide into your product line.

• Common Pitfall: Accepting peptides with purity below 95% can lead to formulation failures and regulatory issues.
• Selection Standard: Always request a sample batch for in-house testing before committing to large orders.
• Buyer Checklist: Verify COA, MSDS, batch traceability, and supplier certifications.

Core Product Advantages

The ss 31 peptide offers distinct advantages over other mitochondrial-targeted peptides, primarily due to its high purity and stability. With a minimum purity of 98%, this peptide ensures that formulations are free from impurities that could compromise efficacy or safety. The lyophilized powder form provides exceptional stability, with a shelf life of over two years when stored correctly, reducing inventory risks for bulk buyers.

Cost performance is another key advantage, as the ss 31 peptide is competitively priced without sacrificing quality. The manufacturing process is optimized for high yield, allowing suppliers to offer attractive pricing for bulk orders. Additionally, technical support is available to assist with formulation challenges, solubility optimization, and regulatory documentation. This combination of purity, stability, cost performance, and support makes the ss 31 peptide a preferred choice for B2B clients in the cosmetic and research sectors.

Frequently Asked Questions

Q1: What is the minimum purity level for ss 31 peptide in bulk orders?
A1: The standard minimum purity for ss 31 peptide in bulk orders is 98% by HPLC. For premium research applications, we offer 99.5% purity with full documentation, including HPLC and MS data.

Q2: How should ss 31 peptide be stored to maintain its stability?
A2: ss 31 peptide should be stored at -20°C in a lyophilized form. For short-term use, it can be kept at 4°C for up to 30 days. Avoid repeated freeze-thaw cycles to preserve activity.

Q3: Can ss 31 peptide be used in cosmetic formulations without additional solubilization?
A3: Yes, ss 31 peptide is fully soluble in water at 10 mg/mL, making it easy to incorporate into aqueous cosmetic formulations. For oil-based products, DMSO can be used as a solvent.